Plasmid DNA
Plasmid DNA is our core competence, either circular or linearized, big or small. With more than 80 individual GMP-manufactured plasmids, we have a strong track record.
Core Competence: pDNA
Comprehensive expertise in pDNA manufacturing:
Biomay has been a specialized GMP plasmid manufacturer since more than a decade. As a service provider, we put high strategic priority on plasmid DNA. Biomay has a deep scientific understanding and a profound problem solving capacity in any context of plasmid manufacturing and testing.
Biomay’s technology offers scalability, comparability, effectiveness, a high yield and attractive pricing throughout the whole product life cycle (from clinical phases I-III to sustained market supply).
Extensive track record in the numerous pDNA products:
- Aseptically filled drug product for gene therapy and DNA vaccination
- Bulk drug substance (API) for gene therapy and DNA vaccination
- Critical starting material:
- viral gene therapies (e.g. starting plasmids for adeno-associated viral / AAV vectors)
- viral cell therapies and CAR-T (e.g. starting plasmids for lentiviral / LV vectors)
- mRNA vaccines (e.g. linear DNA templates for in-vitro transcription)
Special features of Biomay's proprietary plasmid platform
- Generic and universal platform for manufacturing and testing
- Variable and scalable in batch size: from 100 mg to 100 g
- Well suited for big plasmids up to 20 kilo-base pairs
- Well suited for tailored enzymatic linearization (mRNA IVT template)
- Generic quality control methods for circular and linear DNA
- Proven for fast track supply of personalized batches
- Process free of animal components, antibiotics, organic solvents
- High quality, purity and homogeneity
(% supercoiled)
Related Services
From sequence to product
Biomay is your one-stop-shop for GMP manufacturing services.
